Its use and cardiac cell-specific enhancer factor

摘要

(57) [Abstract] The present invention relates to reagents and methods for expressing a gene product in a cardiac cell precursors or heart cells in vivo and in vitro. In addition, the present invention relates to cardiac cell-specific enhancer factor, which is derived from Csx / Nkx2.5 regulatory region. Differentiation into cardiomyocytes (iii) stem cells to regulate gene expression [MEANS FOR SOLVING PROBLEMS] in (i) heart cells, and allowed to differentiate as cardiomyocytes to induce (ii) stem cells (eg, bone marrow stem cells or embryonic stem cells) is to provide a useful enhancer factor To determine factors that induce.