Method for producing fluticasone and related 17-carbothioic acid ester using a novel method for synthesizing carbothioic acid and a novel purification method

摘要

This invention discloses a novel method for the conversion of carboxylic acids to carbothioic acids and application of the method to the preparation of androstane carbothiolates, such as fluticasone propionate, which avoids column chromatography.