Antidepressants or remedies for insulin resistance and / or obesity

摘要

It is an object of the present invention to provide a preventive or improved agent for insulin resistance and / or obesity and methods of screening thereof based on a new concept. It has been found that GIP is responsible for insulin resistance and obesity, and that the compound that inhibits the function of GIP has the insulin resistance improvement action and the antiobesity effect, and the present invention has been completed. That is, the present invention is characterized by the use of a compound that inhibits the function of GIP as an active ingredient and is a preventive agent or an agent of insulin resistance and / or obesity, and selects a compound that inhibits the function of GIP, insulin resistance and / or Is a screening method for the antihypertensive agent or the improvement agent.