Eurea derivative, method for producing the same and pharmaceutical containing the urea derivative

摘要

A urea derivative represented by an H or an alkyl group such as h, a halogen atom, an alkyl group, an aryl group, an arylamide group, y or s, Z is a hydrocarbon group or a heterocyclic group that contains nitrogen atoms and bonds to carbon of C = y through the nitrogen atom, and The salt or the manufacturing method thereof is disclosed. The urea derivative or its salt is a new compound which exhibits VLA-4 antagonist action and is useful as a drug as VLA-4 antagonist.