The use of two quantum 1H-NMR spectroscopy for the identification of ligands that interact with the target biomolecules

摘要

(57) a target biomolecule, such as a screening method rapid and efficient to provide and identify compounds that interact with the therapeutic target bio-molecules such as proteins, [Abstract] The present invention is not the presence of the target biomolecule generates two quantum spectrum two quantum relaxation weighted or two quantization (non refocusing or refocusing) two-dimensional proton mixture of compounds in the standing under the difference between the spectra that indicate the presence of one or more compounds that bind to a target biomolecule and methods for detecting this when there is.