ABCB9 transporter novel and its use

摘要

(57) [summary] The present invention provides (termed ABCB9 transporter nucleic acid molecule) an isolated nucleic acid molecule encoding the ABC transporter family members of the new. The present invention is a host cell into which a recombinant expression vector comprising an antisense nucleic acid molecule, the ABCB9 transporter nucleic acid molecule has been introduced the expression vector, the non-human transgenic destroyed and ABCB9 transporter gene or has been introduced I provides an animal. Still further, ABCB9 transporter isolated protein, fusion proteins, antigenic peptides, anti ABCB9 transporter antibodies, and the invention provides screening assays for modulators ABCB9 transporter. There is also provided a diagnostic and therapeutic methods utilizing compositions of the present invention.