RNA-BINDING PROTEIN MUSASHI2

摘要

PROBLEM TO BE SOLVED: To provide a Musashi 2 (Msi2) protein and an Msi2 gene useful as a reagent for maintaining and proliferating a neuronal precursor cell/a central nervous system stem cell, further as a reagent for producing and/or maintaining a parvalbumin (PV)-containing GABAergic neuronal subpopulation and as a therapeutic agent for various neurological diseases.;SOLUTION: This Msi protein 2 and its gene have a specific amino acid sequence or an amino acid sequence in which one or a plurality of amino acids are substituted, deleted, added or inserted in the amino acid sequence and RNA- binding properties.;COPYRIGHT: (C)2003,JPO