Superfamily receptor chimeras, translocation assay for superfamily receptor ligands, and methods and kits for detecting and characterizing receptor ligands

摘要

The present invention relates to novel superfamily receptor chimeras, methods for using superfamily receptor chimeras, methods and kits for detecting cellular function and metabolic state, and the treatment of disease states involving defective receptor protein cytoplasm/nuclear translocation. In particular, this invention is preferably directed to chimeras of glucocorticoid receptor/superfamily receptor proteins.