Cathepsin differentially expressed in lung cancer

摘要

The invention is a new human cathepsin (LCAP), the cDNAs that encode LCAP, and antibodies that specifically bind LCAP that are used in methods for diagnosing and treating disorders of cell proliferation, particularly lung cancer, as associated with expression of LCAP. The invention provides expression vectors, host cells, and methods for making LCAP and agonists, antibodies and antagonists that specifically bind the protein.