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Cryptosporidium sporozoite antigens

机译：隐孢子虫子孢子抗原

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摘要

Antigenic polypeptides and peptides from Cryptosporidium, and nucleic acid molecules encoding same, are dis-closed which have potential for use in a protective vaccine preparation. A preferred polypeptide has the amino acid sequence, (a). <TableGroup align="left" colSep="0" cols="3" rowSep="0"><Colspec align="left" colName="OFFSET" colWidth="14PT"/><Colspec align="left" colName="1" colWidth="203PT"/><Colspec align="left" colName="2" colWidth="0PT"/><Tbody valign="top"><Row><entry/><entry/></Row><Row><entry/><entry>10203040</entry><entry/></Row><Row><entry/><entry>MRLSLIIVLL SVIVSAVFSA PAVPLRGTLK DVPVEGSSSS</entry></Row><Row><entry/><entry/></Row><Row><entry/><entry>50607080</entry></Row><Row><entry/><entry>SSSSSSSSSS SSSSSSSTSTVAPANKARTG EDAEGSQDSS</entry></Row><Row><entry/><entry/></Row><Row><entry/><entry>90100110120</entry></Row><Row><entry/><entry>GTEASGSQGS EEEGSEDDGQ TSAASQPTTP AQSEGATTET</entry></Row><Row><entry/><entry/></Row><Row><entry/><entry>130140150160</entry></Row><Row><entry/><entry>IEATPKEECG TSFVMWFGEG TPAATLKCGA YTIVYAPIKD</entry></Row><Row><entry/><entry/></Row><Row><entry/><entry>170180190200</entry></Row><Row><entry/><entry>QTDPAPRYIS GEVTSVTFEKSDNTVKIKVN GQDFSTLSAR</entry></Row><Row><entry/><entry/></Row><Row><entry/><entry>210220230240</entry></Row><Row><entry/><entry>SSSPTENGGS AGQASSRSRR SLSEETSEAA ATVDLFAFTL</entry></Row><Row><entry/><entry/></Row><Row><entry/><entry>250260270280</entry></Row><Row><entry/><entry>DGGKRIEVAV PNVEDASKRD KYSLVADDKP FYTGANSGTT</entry></Row><Row><entry/><entry/></Row><Row><entry/><entry>290300310320</entry></Row><Row><entry/><entry>NGVYRLNENGDLVDKDNTVL</entry></Row></Tbody></TableGroup></TableFormula></Table> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span>公开了来自隐孢子虫的抗原性多肽和肽，以及编码它们的核酸分子，其具有用于保护性疫苗制剂的潜力。优选的多肽具有氨基酸序列（a）。<Table id =“ TABLE-US-00001”> <TableFormula> <Title /> <TableGroup align =“ left” colSep =“ 0” cols =“ 3” rowSep =“ 0”> <Colspec align =“ left” colName =“ OFFSET” colWidth =“ 14PT” /> <Colspec align =“ left” colName =“ 1” colWidth =“ 203PT” /> <Colspec align =“ left” colName =“ 2” colWidth =“ 0PT” /> < Tbody valign =“ top”> <行> <entry /> <entry /> </ Row> <Row> <entry /> <entry> 10203040 </ entry> <entry /> </ Row> <Row> <entry /> <entry> MRLSLIIVLL SVIVSAVFSA PAVPLRGTLK DVPVEGSSSS </ entry> </ Row> <Row> <entry /> <entry /> </ Row> <Row> <entry /> <entry> 50607080 </ entry> </ Row > <Row> <entry /> <entry> SSSSSSSSSS SSSSSSSTSTVAPANKARTG EDAEGSQDSS </ entry> </ Row> <Row> <entry /> <entry /> </ Row> <Row> <entry /> <entry> 90100110120 </ entry> </ Row> <Row> <entry /> <entry> GTEASGSQGS EEEGSEDDGQ TSAASQPTTP AQSEGATTET </ entry> </ Row> <Row> <entry /> <entry /> </ Row> <Row> <entry /> <entry> 130140150160 </ entry> </ Row> <Row> <entry /> <entry> IEATPKEECG TSFVMWFGEG TPAATLKCGA YTIVYAPIKD </ entry> </ Row> <Row> <entry /> <entry /> </ Row> <行> <entry /> <entry> 170180190200 </ entry> </ Row> <Row> <entry /> <entry> QTDPAPRYIS GEVTSVTFEKSDNTV KIKVN GQDFSTLSAR </ entry> </ Row> <Row> <entry /> <entry /> </ Row> <Row> <entry /> <entry> 210220230240 </ entry> </ Row> <Row> <entry / > <entry> SSSPTENGGS AGQASSRSRR SLSEETSEAA ATVDLFAFTL </ entry> </ Row> <Row> <entry /> <entry /> </ Row> <Row> <entry /> <entry> 250260270280 </ entry> </ Row> <Row> <entry /> <entry> DGGKRIEVAV PNVEDASKRD KYSLVADDKP FYTGANSGTT </ entry> </ Row> <Row> <entry /> <entry /> </ Row> <Row> <entry /> <entry> 290300310320 </ entry> </ Row> <Row> <entry /> <entry> NGVYRLNENGDLVDKDNTVL </ entry> </ Row> </ Tbody> </ TableGroup> </ TableFormula> </ Table> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33">著录项</h2> <div class="getdents"> <ul> <li> <p><span>公开/公告号</span><span>US2003185836A1</span></p> <p><span>专利类型</span><span></span></p> </li> <li> <p><span>公开/公告日</span><span>2003-10-02</span></p> <p><span>原文格式</span><span>PDF</span></p> </li> <li> <div class="apply"> <p><span style="width: 90px;display: inline-block;">申请/专利权人</span><span id="patentee" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=12_13&sertext=WINTER GERHARD&option=232">WINTER GERHARD;</a><a href="/search.html?doctypes=12_13&sertext=SLADE MARTIN BASIL&option=232">SLADE MARTIN BASIL;</a><a href="/search.html?doctypes=12_13&sertext=WILLIAMS KEITH LESLIE&option=232">WILLIAMS KEITH LESLIE;</a><a href="/search.html?doctypes=12_13&sertext=GOOLEY ANDREW ARTHUR&option=232">GOOLEY ANDREW ARTHUR;</a> </span></p> <span class="designer hoverxs" style="display: none;">展开▼</span> </div> <p><span>申请/专利号</span><span style="width: 250px;">US20030148687</span></p> </li> <li> <div class="apply"> <p><span style="width: 90px;display: inline-block;">发明设计人</span><span id="patentee" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=12_13&sertext=GERHARD WINTER&option=202">GERHARD WINTER;</a><a href="/search.html?doctypes=12_13&sertext=MARTIN BASIL SLADE&option=202">MARTIN BASIL SLADE;</a><a href="/search.html?doctypes=12_13&sertext=KEITH LESLIE WILLIAMS&option=202">KEITH LESLIE WILLIAMS;</a><a href="/search.html?doctypes=12_13&sertext=ANDREW ARTHUR GOOLEY&option=202">ANDREW ARTHUR GOOLEY;</a> </span></p> <span class="designer hoverxs" style="display: none;">展开▼</span> </div> <p><span>申请日</span><span>2003-04-09</span></p> </li> <li> <p style="width: 100%;"><span>分类号</span><span style="width: 80%;">A61K39/00;A61K39/38;A61K39/002;</span> </p> </li> <li> <p style="width: 100%;"><span>国家 </span><span style="width: 93%;">US</span></p> </li> <li><p style="width: 100%;"> <span >入库时间</span> <span>2022-08-22 00:09:10</span></p> </li> </ul> </div> </div> </div> <div class="literature cardcommon"> <div class="similarity"> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul > <li >专利</li> <li >外文文献</li> <li >中文文献</li> </ul> </div> <div class="similarity_details"> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" 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<div> <b>7. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/040001468178.html">Age-specific seroprevalence to an immunodominant Cryptosporidium sporozoite antigen in a Brazilian population.</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=1_2_3_4_5_6_7_1-0_9_4-0&sertext=M. 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