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Novel molecules of the PYRIN domain protein family and uses thereof
Novel molecules of the PYRIN domain protein family and uses thereof
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机译:PYRIN结构域蛋白家族的新型分子及其用途
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摘要
Diagnostic, screening and therapeutic methods utilizing NBS-1 and PYRIN-1 are disclosed. The methods take advantage of the interactions between NBS-1 or PYRIN-1 and various proteins involved in apoptotic and inflammatory signaling pathways. Also disclosed are methods for identifying modulators of ASC and NF-&kgr;B.
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