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Method of blocking cytotoxic activity in patients with amyotrophic lateral sclerosis using antibodies to Fcamp;ggr;RIII
Method of blocking cytotoxic activity in patients with amyotrophic lateral sclerosis using antibodies to Fcamp;ggr;RIII
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机译:使用针对Fc&ggr; RIII的抗体阻断肌萎缩性侧索硬化症患者细胞毒性活性的方法
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摘要
The present invention is directed to a method of blocking the cytotoxic activity of Fc&ggr;RIII receptor-positive immune cells in a patient with amyotrophic lateral sclerosis using antibodies specific for Fc&ggr;RIII receptor. In one aspect, the antibody may be a monoclonal antibody. In another aspect, the antibody or the monoclonal antibody may be conjugated with a cytotoxic substance. In a further aspect, the antibody binds to the Fc&ggr;RIII receptor, inactivates the receptor, and destroys cellular forms containing the receptor.
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