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Human cGMP-stimulated cyclic nucleotide phosphodiesterase
Human cGMP-stimulated cyclic nucleotide phosphodiesterase
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机译:人cGMP刺激的环状核苷酸磷酸二酯酶
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摘要
The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding recombinant expression products of said nucleotide sequences, immunological reagents specifically reactive therewith, and procedures for identifying compounds which modulate the enzymatic activity of such expression products.
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