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Snail, new tumoral progression marker and target protein of new antitumoral compounds

机译:蜗牛,新的肿瘤进展标志物和新的抗肿瘤化合物的靶蛋白

摘要

The Snail transcription factor has been identified as a repressor of the expression of E-cadherin. The expression of Snail induces invasive and metastatic capacity in tumor cells. This invention presents: a new target protein, Snail, for the identification of new antitumoral compounds and a new diagnostic tumor marker, indicative of tissue invasion and metastatic capacity.
机译:Snail转录因子已被鉴定为E-钙粘蛋白表达的阻遏物。 Snail的表达诱导肿瘤细胞的侵袭和转移能力。本发明提出了一种新的靶蛋白,Snail,用于鉴定新的抗肿瘤化合物和新的诊断性肿瘤标志物,其指示组织侵袭和转移能力。

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