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FADD-like anti-apoptotic molecules, methods of using the same, and compositions for and methods of making the same
FADD-like anti-apoptotic molecules, methods of using the same, and compositions for and methods of making the same
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机译:类似于fadd的抗凋亡分子,其使用方法,及其组合物和制备方法
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摘要
Two FADD-like anti-apoptotic proteins that regulate Fas/TNFR1- or UV-induced apoptosis are disclosed. Nucleotide sequences encoding the proteins are disclosed as are methods of using the nucleic acid molecules and making the proteins. Pharmaceutical compositions and methods of using the same are disclosed. Reagents, kits and methods of identifying compounds that inhibit anti-apoptotic activity of the proteins and methods of identifying compounds that inhibit binding activity of the proteins are disclosed.
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