Preparation of blisters modified by Genetic Engineering bacterial Strain isolated from a Gram negative Neisseria meningitidis, Moraxella catarrhalis and Haemophilus influenzae,Vaccines that include Gram negative bacterial strain and Method for preparing the Vaccine and its use for High School

摘要

Vaccine vials and Gram negative immunoprotective non-toxic suitable for Pediatric use. Examples of Gram negative strains which are prepared lasampollas N.Meningitidis, M. catarrhalis and H. influenzae.The blisters of the invention ejoran sem by one or more genetic changes on chromosome of bacteria, including upregulation of Protective antigens.Subrregulacion immunodominant antigens not Protectors and detoxification appropriate Lipid A of LPS.