Pharmaceutical compositions having an immediate release phase and a phase of sustained release of paracetamol (Cetyl - N - P - aminofenoli)

摘要

These Pharmaceutical compositions comprising an instantaneous Release phase and a phase of sustained release of paracetamol (N - acetyl - P - Aminophenol) that has a Dissolution profile inResults in vitro only advantageous pharmacokinetic iedades Prop.These compositions have a secaracterizan by in vitro Dissolution Profile (determined with the device USP Type III, with basket swing and 250 ml of 0.1 m HCl to 37 degree C TEMPERATURE,Set at a Speed of Cycle Racing / 15 min) with the following limitations: - 30 to 48% released after 15 minutes, - 56 to 75% released after 60 minutes; increased 85% released afterIT 180 minutes.