Method for preparing ACID 6 - (4-chlorophenyl) - 2,2-dimethyl - phenyl - 2 - 7,Dihydro - 1 - 3 - 5 - il pirrolizin acid by pirrolico Ring formation by Reduction with ni raneydel corresponding Nitrile derivative.

摘要

The Invention relates to a process for the preparation of Acid 6 - (4-chlorophenyl) - 2,2 - Dimethicone - 7 - phenyl - 2,3 dihydro - 1H - pirrolizin - 5 - il - acetic acid, in which Transforms - Benzyl - 5 33 - dimethyl - 3,4-dihydro - 2H pyrrole with W - Bromine - 4 - CHLOROACETOPHENONE 54 under formation of 6 - (4-chlorophenyl) - 2,2-dimethyl - phenyl - 2 - 7,3 - dihydro 1h pirrolizina and introduces the acetic acid Group in position 5, obtenendose there 5 - Benzyl - 3,3-dimethyl - 3,4-dihydro - 2H pyrrole by hydrogenation of 2,Dimethyl 2 - oxo - 5 - 4 - phenyl - valeronitrilo or ketal.The Invention also relates to a process for the preparation of Intermediates that appear in the procedure mentioned above.