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Noninvasive transdermal Systems for Detecting Biological and Analytical Methods in a Fluid

机译:用于检测液体中生物和分析方法的无创透皮系统

摘要

The present Invention relates to systems and Methods for non-invasive transdermal extraction of analytes from a Biological Fluid within or under the skin, such as Interstitial Fluid,And detection of the analyte. More particularly, the present Invention relates to Noninvasive transdermal Systems comprising a non-invasive Patch and a Reflectometer.Noninvasive transdermal patches are comprised of a Wet Chemistry Component and a Dry Chemistry component.The Wet Chemistry component is a Liquid Transfer Medium in the form of a gel Layer for the transfer of liquid extraction and bridged the analyte of interest biolu00f3gic FluidOr within or Beneath the skin to Dry Chemistry component.The Dry Chemistry component is a Membrane Structure which has a sensitive and reactive system to interact with the analyte of interest to generate a Molecule indicatorEg: Color Change, to confirm the detection of the analyte, and Methods for using the same.The Indicator Molecule can be observed visually by the user or observed by a component of electronic interpretation as a Reflectance Spectrophotometer for Detection.An analyte of interest in particular can be detected accurately, reliably and quantitatively according to the present Invention is Glucose.Noninvasive transdermal Systems of the present Invention are economical and suitable for convenient use by non-medical personnel. ...File = " EMI 00018126 _ 1" mfi id = "1" = invenciu00d3nordenadas JPEG Patent Applications published in January 2003 importantesolicitudes Patent of Invention: from the date of publication dThis Gazette and the applicant has a period of six months to apply to take the examination of Patent ApplicationAttach the receipt of payment of the fee for this purpose. The application will not be abandoned (art. 44 of Decision 486).
机译:本发明涉及用于从皮肤内或皮肤下的生物流体(诸如间质液)中非侵入性透皮提取分析物以及检测分析物的系统和方法。更具体地,本发明涉及包括非侵入性贴剂和反射计的非侵入性透皮系统。非侵入性透皮贴剂由湿化学成分和干化学成分组成。湿化学成分是呈以下形式的液体转移介质:凝胶层,用于转移液体萃取物,并将感兴趣的分析物,生物流体或皮肤内或皮肤之间桥接至干化学成分。干化学成分是具有敏感和反应性系统的膜结构,可与被分析物相互作用。生成分子指示剂的兴趣例如:颜色变化,以确认分析物的检测方法以及使用该方法的指标指示剂分子可以由用户目测观察,也可以通过电子解释的组件作为检测用反射分光光度计进行观察。可以根据t值准确,可靠和定量地检测目标分析物本发明是葡萄糖。本发明的非侵入性透皮系统是经济的并且适合于由非医务人员方便地使用。 ...文件= “ invenci u00d3nordenadas于2003年1月发布的JPEG专利申请重要声明发明专利:自d发行之日起,该宪报和申请人拥有在六个月的时间内申请参加专利申请审查。为此目的,请附上收款费用的收据。该申请将不会被放弃(第486号决定第44条)。

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