N-(5-{(5-Alkyl-2-oxazolyl)methylthio}-2-thiazolyl) carboxamides functioning as cyclin-dependent kinase inhibitors

摘要

The present invention describes compound of formula I and its enantiomer, diastereomer, solvate and pharmaceutically acceptable salt. The formula compound is kinases inhibitor, can be used for treating proliferative disease, such as cancer, inflammation and arthritis. They can also be used in the alopecia and cardiovascular disease for the treatment of Alzheimer disease, chemotherapy induction.