N-(5-{(5-Alkyl-2-oxazolyl)methylthio}-2-thiazolyl) carboxamides functioning as cyclin-dependent kinase inhibitors

摘要

The present invention describes compounds of the formula: and enantiomers, diasteromers, solvates, and pharmaceutically acceptable salts thereof. The formula compounds are protein kinase inhibitors and are useful in the treatment of proliferative diseases, for example, cancer, inflammation and arthritis. They may also be useful in the treatment of Alzheimer's disease, chemotherapy-induced alopecia, and cardiovascular disease.