Quinoline and quinazoline compounds useful in therapy especially for the treatment of benign prostatic hyperplasia

摘要

Compounds of formula I,whereinR1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms;R2 represents H or C1-4 alkoxy optionally substituted by one or more fluorine atoms;R3 represents a 5- or 6-membered heterocyclic ring, the ring being optionally substituted;R4 represents a 4-, 5-, 6-, or 7-membered heterocyclic ring, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring, the ring system as a whole being optionally substituted;X represents CH or N; andL is absent, or represents a cyclic group of formula Ia, or represents a chain of formula Ib,and pharmaceutically acceptable salts thereof; are useful in therapy, in particular in the treatment of benign prostatic hyperplasia.