首页>
外国专利>
Delayed release formulations of oral tablets containing 3 - (3-dimethylamine-1-ethyl-2-methyl-propyl) phenol or a pharmaceutically acceptable salt and containing such phenol
Delayed release formulations of oral tablets containing 3 - (3-dimethylamine-1-ethyl-2-methyl-propyl) phenol or a pharmaceutically acceptable salt and containing such phenol
In a matrix containing 1% to 80% of one or more water balls or water fobos polymers as the acceptable matrix of the drug, and the release rate displayed in the test tube, measured by the paddy Ph.Eur method. At a pressure of 6.8 to 37 degrees C, use the UV spectrum detection device for 75 revolutions per minute. The release rate of 3 - (3-dimethylamine-1-ethyl-2-methylpropyl) phenol was measured at 100% of the weight of the active substance: (a) 3-35% after 0.5 h; (b) 5-50% after 1 h; (c) 10-75% after 2 h; (d) 15-82% after 3 h;(e) 39% to 97% after 6 h; (f) more than 50% after 12 h; (g) more than 70% after 18 h; (H) more than 80% after 24 h
展开▼