COMPOSITIONS OF ACICLOVIR CONTAINING DIMETICONE

摘要

Topical pharmaceutical formulation comprising aciclovir, dimethicone and at least 30 w/w % of a water miscible polyhydric alcohol, is new. Independent claims are also included for: (1) an oil-in-water pharmaceutical formulation comprising water, solubilized aciclovir, dimethicone and at least 30 w/w % of a water-miscible polyhydric alcohol, as well as a continuous aqueous phase in which is dispersed an oil phase; (2) use of aciclovir, dimethicone and at least 30 w/w % of a water miscible polyhydric alcohol in the preparation of a topical medicament for treating herpes family viral infections; (3) use of dimethicone in decreasing irritancy of topical oil-in-water formulations comprising at least 30 w/w % of a water-miscible polyhydric alcohol. ACTIVITY : Antiviral. MECHANISM OF ACTION : None given.