Method for the simplified production of (3-chloro-4-fluorophenyl)-7-(3-morpholino-4-yl-propoxy)-6-nitro-quinazoline-4-yl-amine or (3-chloro-4-fluoro-phenyl)-7-(3-morpholino-4-yl-propoxy)-6-amino-quinazoline-4-yl-amine.

摘要

The invention concerns a one-pot reaction for the preparation of (3-chloro-4-fluorophenyl)-[7-(3-morpholin-4-yl-propoxy)-6-nitroquinazolin-4-yl]-amine (I) or of (3-chloro-4-fluorophenyl)-[7-(3-morpholino-4-yl-propoxy)-6-aminoquinazolin-4-yl]-amine (VII)