POLYMER LAMELAR SUBSTRATE PARTICLES FOR THE ADMINISTRATION OF PHARMACOS.

摘要

THE INVENTION PROVIDES A COMPOSITION FOR THE ADMINISTRATION OF AN ACTIVE AGENT THAT CONSISTS OF VARIOUS LAMELARY PARTICLES OF A BIODEGRADABLE POLYMER, WHICH IS AT LEAST IN CRYSTAL PART, AND OF AN ACTIVE AGENT ADSORBED AT LEAST MOST OF THE PARTICLES. PREFERENTLY, THE BIODEGRADABLE POLYMER IS CRYSTALLINE AT LEAST 5% OF THE WEIGHT. THE PREFERRED BIODEGRADABLE POLYMERS ARE POLI (L - LACTIDE) (L.PLA) OR COPOLIMEROS OR MIXTURES OF L.PLA. THE PARTICLES ARE ESPECIALLY USEFUL FOR THE IMMOBILIZATION OF ANTIGENS OR ALLERGENS FOR VACCINES.