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TOPICAL TREATMENT AND/OR PREVENTION OF SAGGING SUBCUTANEOUS MUSCLE AND OVERLYING CUTANEOUS TISSUE USING ACETYLCHOLINE PRECURSORS AND CATECHOLAMINES
TOPICAL TREATMENT AND/OR PREVENTION OF SAGGING SUBCUTANEOUS MUSCLE AND OVERLYING CUTANEOUS TISSUE USING ACETYLCHOLINE PRECURSORS AND CATECHOLAMINES
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机译:使用乙酰胆碱前体和儿茶酚胺进行局部治疗和/或预防下垂肌和上皮组织的治疗
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摘要
Compositions for the topical treatment of sagging subcutaneous muscle andoverlying cutaneous tissue containing catecholamines and/or acetylcholineprecursors in a dermatologically acceptable carrier. Catecholamines includeadrenaline, norepinepherine, dopamine and their precursors; catecholamineprecursors such as tyrosine and phenylalanine are preferred. Acetylcholineprecursors include dimethylaminoethanol, monoaminoethanol, choline, serine,and mixtures thereof. Preferred embodiments further contain at least one otheringredient that enhances skin penetration. In these and other embodiments,particularly those employing tyrosine and/or phenylalanine as a catecholamineprecursor, other cofactors such as vitamin B6 and pantothenic acid or calciumpantothenate are included in the composition to enhance the action of theactive ingredients. Other compounds that scavenge free radicals andantioxidants may also be added; a fatty acid ester of ascorbic acid isincluded in some formulations.
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