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ENHANCING ORGAN MATURITY IN NEONATES AND PREDICTING THEIR DURATION OF INTENSIVE CARE
ENHANCING ORGAN MATURITY IN NEONATES AND PREDICTING THEIR DURATION OF INTENSIVE CARE
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机译:增强新生儿的器官成熟度并预测其密集护理的时间
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摘要
The present invention is directed to methods of enhancing organ maturity ofpremature human neonates or increasing collagen type IV formation in a livingsystem by administering a growth factor, a gene encoding a growth factor, oran agent that increases growth factor formation to the living system underconditions effective to increase collagen type IV formation. Another aspect ofthe present invention relates to a method of predicting a premature humanneonate's length of stay in a neonatal intensive care unit as well as theanticipated medical costs incurred during said stay by providing a sample fromthe premature human neonate and determining biomarkers derived from theextracellular matrix in the sample. The biomarker levels or ratios thereof inthe sample are compared to a standard to ascertain the premature humanneonate's length of stay in a neonatal intensive care unit as well as theanticipated medical costs incurred during said stay.
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