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METHODS FOR DIAGNOSING AND TREATING NEOPLASIAS USING NF-AT TRANSCRIPTION FACTORS

机译:NF-at转录因子诊断和治疗恶性肿瘤的方法

摘要

Described is a method for diagnosing a neoplasia by determining whether thelevel of one or more NF-AT transcription factor(s) is reduced. Moreover,methods for screening compounds which activate an NF-AT or which mimic thefunction of NF-AT are disclosed. Also disclosed are methods for the preventionor treatment of neoplasias by increasing the activity of an NF-AT.
机译:描述了一种通过确定是否存在肿瘤来诊断瘤形成的方法。一种或多种NF-AT转录因子的水平降低。此外,筛选可激活NF-AT或模拟NF-AT的化合物的方法公开了NF-AT的功能。还公开了预防方法或通过增加NF-AT的活性来治疗肿瘤。

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