METHOD FOR DIAGNOSING AND TREATING PREDISPOSITION FOR ACCELERATED AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE

摘要

Present invention provides a method for diagnosing a predisposition for accelerated autosomal dominant polycystic kidney disease (ADPKD) in a human male subject by detecting the Glu 298 Asp polymorphism of the ENOS gene. Present invention also provides a diagnostic kit for detecting predisposition for accelerated ADPKD in human subject. In addition, present invention provides a method for treating a human subject predisposed to develop accelerated APDKD using NO-enhancing compounds.