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Method and device for automated chromophore-assisted laser/light inactivation (CALI)
Method and device for automated chromophore-assisted laser/light inactivation (CALI)
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机译:自动生色团辅助的激光/光灭活(CALI)的方法和设备
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摘要
In the process, the irradiated ligand coupling partner (LBP)-tag selectively modifiers the bound ligand, and the sequence stages can be changed. Process for identification of function of ligands L, where the chromophore-support laser inactivation (CSLI) are used, involves (a) calculation of one ligand bonding partner with specifiate for the ligand L, (b) coupling of LBP on a laser activation marker (tag) during formation of LBP-tag, optionally after modification of the LBP with respect to an efficient bonding to the marker, (c) contacting of ligand L with at least one LBP-tag forming of L/LBP-tag-complex and (d) irradiation of LBP-tag-complex with a laser beam.
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