Expressing GP140 fragment of primary HIV-1 isolate

摘要

A vector for eliciting an immune response to a host comprising a gene encoding the gp140 protein of the primary isolate of HIV-1, BX08, under the control of a promotor for expression of the protein in the host, specifically plasmid pCMV.gp140.BX08. Murine and human MHC class 1-restricted binding motifs contained in BX08 are identified.