Gaba-A receptor subunits (alpha-2, alpha-3, alpha-5, alpha -6, beta-2) and transfected cells expressing them

摘要

The present invention relates to a stably co-transfected eukaryotic cell line capable of expressing a GABAA receptor, particularly a human GABAA receptor, which receptor comprises at least one alpha, one beta and one gamma subunit; to the cloning of novel cDNA sequences encoding the (α-2, α-3, α-5, α-6 and β-2 subunits of the human GABAA receptor; and to the use of the cell line in designing and developing GABAA receptor subunit-selective medicaments.