NUCLEIC ACID CODING FOR THE HUMAN TESTICULAR ANGIOTENSIN CONVERSION ENZYME (ECA) AND ITS APPLICATIONS, IN PARTICULAR FOR THE IN VITRO DETECTION OF SAID ENZYME IN THE ORGANISM

摘要

The object of the invention is the cloning and sequencing of the nucleic acid coding for the human testicular ACE as well as the determination of the peptide sequence of this ACE. It relates more particularly to the use of nucleotide probes capable of hybridizing with all or part of the above-mentioned nucleic acid, and also the polyclonal or monoclonal antibodies recognizing specifically all or part of the above-mentioned peptide sequence, and the use of these probes or these antibodies for the implementation, respectively, of a method for the detection of the messenger RNA coding for the testicular ACE in vitro or of the testicular ACE directly.