首页>
外国专利>
LOCALLY ADMINISTRABLE, BIODEGRADABLE AND SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION FOR PERIODONTITIS AND PROCESS FOR PREPARATION THEREOF
LOCALLY ADMINISTRABLE, BIODEGRADABLE AND SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION FOR PERIODONTITIS AND PROCESS FOR PREPARATION THEREOF
展开▼
机译:用于牙周病的局部可消化,生物可降解和缓释药物成分及其制备方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention relates to locally administrable, biodegradable and sustained-release pharmaceutical composition for periodontitis and process for preparation thereof, which can show continuous drug effect for a long time by controlling the release time and by making the drug remain in the periodontal pocket for a prolonged time. The composition is prepared by i) making a microsphere containing the physiologically active substance, ii) making the mixture of the microspheres and water-soluble polymer such as polysaccharides iii) making the mixture into the form of film or strip or/and iv) coating the film or strip with a cation aqueous solution such as calcium and barium.The present pharmaceutical composition can be easily administered using forceps, has minimized side effects and maximizes the effect by releasing the active substance at the minimum dose, and make the patients feel comfortable.
展开▼