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METHOD OF DETECTING MUTATION IN HUMAN SEROTONIN RECEPTOR SUBTYPE 2B GENE

机译:检测人类血清素受体2B亚型基因突变的方法

摘要

It is intended to provide DNA of a human serotonin receptor subtype 2B gene having a novel mutation. It is also intended to provide a method of detecting a mutation in the human serotonin receptor subtype 2B gene using the novel mutation as described above. Namely, (1) a DNA having a mutation of the base at the 1162-position in the code domain of human serotonin receptor subtype 2B gene into thymine (T); or (2) a DNA being derived from the above DNA by partial modification in a site other than the above base and having such a base length as allowing the detection of the mutation at the above-described base position. A mutation in the human serotonin receptor subtype 2B gene is detected by a method involving the step (a) of analyzing the base at the 1162-position in the code domain of human serotonin receptor subtype 2B gene.
机译:目的是提供具有新突变的人血清素受体亚型2B基因的DNA。还旨在提供一种使用如上所述的新型突变检测人血清素受体亚型2B基因突变的方法。即,(1)将人5-羟色胺受体2B亚型基因的密码结构域的1162-位碱基突变为胸腺嘧啶(T)的DNA。 (2)通过在上述碱基以外的部位进行部分修饰而衍生自上述DNA的DNA,其碱基长度允许检测上述碱基位置的突变。通过涉及步骤(a)分析人血清素受体2B亚型2B基因密码域中1162-位碱基的方法检测人血清素2B亚型基因的突变。

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