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ETHYL CELLULOSE-CONTAINING VETERINARY SUSTAINED RELEASE INJECTION

机译:含乙基纤维素的兽用缓释注射液

摘要

A veterinary sustained release injection comprises of ethyl cellulose (EC) and therapeutical drugs. The injection characterizes that EC doesn't disperse in form of drug-loading particles, such as microspheres or microcapsules present in the medium of the injection, but dissolves or swells in the medium. When it contacts with water or fluid, hydrophorbic drug present in it combines with EC to form semisolid mass. Thus, the diffusion of active ingredients is limited to achieve sustained release. The present formulation is suitable for subcutaneous injection with slow release in a long period.
机译:兽用缓释注射液包含乙基纤维素(EC)和治疗药物。注射剂的特征在于EC不会以载药颗粒(例如注射剂介质中存在的微球或微胶囊)的形式分散,而是在介质中溶解或溶胀。当它与水或液体接触时,其中存在的疏水性药物会与EC结合形成半固体。因此,有效成分的扩散受到限制以实现持续释放。本制剂适用于长期缓慢释放的皮下注射。

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