NOVEL CHIRAL SALEN CATALYSTS, AND A PROCESS FOR PREPARING CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES FOR USING THEM

摘要

PURPOSE: Provided is a novel chiral salene catalyst which maintains activity even after completing reaction and affect the ramification of chiral epoxide. Also, a method for manufacturing chiral compound using the catalyst is provided. CONSTITUTION: The novel chiral salene catalyst of the formula (1) is manufactured by reacting a salene compound of the formula (2) with cobalt (II) acetate and a ferrocenium derivative in the presence of organic solvent. In the formula (1), X1, X2, X3, X4, X5, X6, X7, and X8 are hydrogen atoms or alkyl groups of C4-C10; Y1 and Y2 are hydrogen atoms or alkyl groups of C1-C5; Z is PF6 or BF4; R1 and R2 are hydrogen atoms, alkyl groups of C4-C10, unsubstituted phenyl groups, or phenyl groups substituted with alkyl groups of C1-C4. And the method for manufacturing chiral epoxide or chiral compound of chiral 1,2-diol is characterized by the use of chiral salene catalyst.