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Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications

机译:吡啶鎓衍生物在化妆品和治疗应用中的组合物和使用方法

摘要

The invention discloses a new class of compounds particularly pyridinium derivatives, which have been found to exhibit triple function of a free radical scavenger (antioxidant), AGE breaker and AGE inhibitor, and cosmetic composition comprising these compounds contained in a cosmetically acceptable carrier. The invention also discloses a method of cosmetic application by applying such composition. The invention further discloses a pharmaceutical composition, comprising said compounds useful in scavenging free radicals from the body cells of a mammal, a method of scavenging free radicals from the body cells of a mammal and a method of treating of diseases caused by accumulation of free radicals in the body cells of a mammal by administering a composition made with the compounds of the invention. The invention in addition, also discloses composition and method for inhibiting AGE in a mammal by use of the compounds of the same group.
机译:本发明公开了新型化合物,特别是吡啶鎓衍生物,已发现它们表现出自由基清除剂(抗氧化剂),AGE破坏剂和AGE抑制剂的三重功能,以及包含这些化合物的化妆品组合物,所述化合物包含在化妆品可接受的载体中。本发明还公开了通过施用这种组合物的化妆品施用方法。本发明进一步公开了一种药物组合物,其包含用于清除哺乳动物的体细胞自由基的所述化合物,清除哺乳动物的体细胞自由基的方法以及治疗由自由基累积引起的疾病的方法。通过施用用本发明的化合物制成的组合物,可以在哺乳动物的体内细胞中释放维生素C。另外,本发明还公开了通过使用相同组的化合物来抑制哺乳动物中AGE的组合物和方法。

著录项

  • 公开/公告号EP1304101A1

    专利类型

  • 公开/公告日2003-04-23

    原文格式PDF

  • 申请/专利权人 TORRENT PHARMACEUTICALS LTD;

    申请/专利号EP20010204295

  • 发明设计人 SANKARANARAYANAN ALANGUDI;

    申请日2001-11-12

  • 分类号A61K7/48;A61K31/44;A61P17/00;

  • 国家 EP

  • 入库时间 2022-08-21 23:49:59

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