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P53-DEPENDENT NOVEL APOPTOSIS-ASSOCIATED PROTEIN AND METHOD OF SCREENING APOPTOSIS CONTROLLING AGENT
P53-DEPENDENT NOVEL APOPTOSIS-ASSOCIATED PROTEIN AND METHOD OF SCREENING APOPTOSIS CONTROLLING AGENT
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机译:P53依赖性新凋亡相关蛋白和凋亡控制剂的筛选方法
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摘要
A novel apoptosis-associated gene p53AIPI is isolated by screening for a gene the expression of which is induced by p53. Since the protein encoded by this gene has an activity of inducing apoptosis, this gene is useful in developing effective therapeutic agents for cancer mediated by apoptosis. A method of screening for a compound controlling the induction of apoptosis which is expected as being useful in developing an apoptosis controlling agent.
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