A TREATMENT OF OESOPHAGEAL MOTILITY DISORDERS AND GASTRO-OESOPHAGEAL REFLUX DISEASE

摘要

Smooth muscle tone modulator compositions and methods of use thereof are provided for the treatment of oesophageal motility disorders and gastro-oesophageal reflux disease. The smooth muscle tone modulators are applied topically to treat the disorder. Topical treatment reduces the risk of undesirable side effects observed in connection with oral or sublingual administration of the modulators.