TWO-COMPONENT ANTI-EMETIC COMPOSITION COMPRISING DEXAMETHASONE AND METOCLOPRAMIDE

摘要

The invention relates to an anti-emetic composition containing dexamethasone (DEX) and metoclopramide (MTC). In a particular embodiment, a composition containing DEX:MTC in a relative weight ratio of about 1 to less than 1.25 is found to be effective in providing relief from the discomfort caused by symptoms of both vomiting and nausea in all patients receiving the composition. Alternatively, an effective suppository composition may contain DEX:MTC in a relative weight ratio of about 1:1-12.5. Other effective compositions and methods of their use are also disclosed.