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-1 41 - ANTIBODY BINDING TO THE N-TERMINAL OF HIV GP41
-1 41 - ANTIBODY BINDING TO THE N-TERMINAL OF HIV GP41
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机译:-1 41-与HIV GP41 N末端结合的抗体
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摘要
PURPOSE: Antibodies specifically binding to the N-terminal of HIV gp 41 are provided, thereby function of gp41 which is essential for the infection of HIV can be inhibited, so that it can be useful for prevention and treatment of HIV. CONSTITUTION: The antibodies which are specifically binding to the N-terminal of HIV gp 41, are capable of recognizing gp 41-ex(extracellular domain), and inhibit function of gp 41 are provided, wherein the heavy chain of an antibody has the amino acid sequences of SEQ ID NO: 1 and the light chain of the antibody has the amino acid sequence of SEQ ID NO: 2; the heavy chain of an antibody has the amino acid sequences of SEQ ID NO: 3 and the light chain of the antibody has the amino acid sequence of SEQ ID NO: 4; the heavy chain of an antibody has the amino acid sequences of SEQ ID NO: 5 and the light chain of the antibody has the amino acid sequence of SEQ ID NO: 6; and the heavy chain of an antibody has the amino acid sequences of SEQ ID NO: 7 and the light chain of the antibody has the amino acid sequence of SEQ ID NO: 8.
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机译:目的:提供特异性结合HIV gp 41 N末端的抗体,从而可以抑制gp41对HIV感染至关重要的功能,从而可用于预防和治疗HIV。组成:特异性结合HIV gp 41 N端的抗体,能够识别gp 41-ex(胞外域),并抑制gp 41的功能,其中抗体的重链具有氨基SEQ ID NO:1的氨基酸序列和抗体的轻链具有SEQ ID NO:2的氨基酸序列。抗体的重链具有氨基酸序列SEQ ID NO:3,抗体的轻链具有氨基酸序列SEQ ID NO:4。抗体的重链具有氨基酸序列SEQ ID NO:5,抗体的轻链具有氨基酸序列SEQ ID NO:6。抗体的重链具有SEQ ID NO:7的氨基酸序列,抗体的轻链具有SEQ ID NO:8的氨基酸序列。
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