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Pharmaceutical agent containing polysaccharide obtained from mycelium of Phellinus linteus against lung cancer

机译:从桑黄菌丝体中获得的含有多糖的抗肺癌药物

摘要

PURPOSE: A composition containing as an active ingredient, (1,6)-heteroglycan and galactomannoglucan is provided. The composition selectively exhibits cytotoxicity to lung cancer cells and is thus used as a pharmaceutical composition for the treatment of lung cancer. CONSTITUTION: The pharmaceutical composition contains (1,6)-heteroglycan and galactomannoglucan having a molecular weight of 153,000 daltons as immunologically active polysaccharides. The (1,6)-heteroglycan(Mesima) and galactomannoglucan(Mesima PL-2) are obtained by extracting and purifying the mycelium of Phellinus linteus(KCTC 0173BP) and (KCTC 0399BP). The effective dose of the Mesima and Mesima PL-2 is 10 to 25mg/kg.
机译:目的:提供一种组合物,其包含作为活性成分的(1,6)-杂聚糖和半乳甘露聚糖。该组合物选择性地表现出对肺癌细胞的细胞毒性,因此用作治疗肺癌的药物组合物。组成:药物组合物含有(1,6)-杂聚糖和半乳甘露聚糖,其分子量为153,000道尔顿,具有免疫活性。 (1,6)-杂聚糖(Mesima)和半乳甘露聚糖(Mesima PL-2)是通过提取和纯化桑黄菌丝体(KCTC 0173BP)和(KCTC 0399BP)获得的。 Mesima和Mesima PL-2的有效剂量为10至25mg / kg。

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