16-substituted-4-aza-androstan5-alpha-reductase isozyme 10 inhibitor

摘要

Compounds of formula (I) are inhibitors of 5α-reductase 1 isozyme and are used alone or in combination with 5α-reductase 2 inhibitors to prevent vulgaris, seborrhea, gynecomastia, male baldness and benign prostatic hyperplasia This is useful for treating androgen-sensitive diseases.