-1 METHOD FOR QUANTIFYING ACTIVE TRANSFORMING GROWTH FACTOR-BETA1 IN BODY FLUID AND METHOD FOR DETECTING CANCER BY USING SAME

摘要

The present invention relates to a method for quantitatively and sensitively measuring transforming growth factor-beta 1 (TGF-β1) identified as a significantly increasing factor in a cancer sample. Adding a sample comprising TGF-β1 to a receptor that specifically binds to TGF-β1 to form a TGF-β1-receptor complex and detecting the TGF-β1-receptor complex using a TGF-β1-specific antibody It relates to a method for quantifying TGF-β1. In addition, the present invention relates to a method for testing cancer, comprising quantifying TGF-β1 in human body fluid, a monoclonal antibody having high specificity for TGF-β1, and a hybridoma cell line producing the same.;According to the TGF-β1 quantification method of the present invention, not only can TGF-β1 be sensitively quantitated, but also human body fluids as a source of TGF-β1 can be used to test cancer with high accuracy by sensitive quantification of TGF-β1. can do.