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METHOD FOR MODELLING THE STATE OF THERMAL SHOCK IN LABORATORY ANIMALS IN VIVO FOR SUBSEQUENT STUDY OF RENAL METABOLISM

机译:后续研究肾脏代谢的模拟实验室动物热休克状态的方法

摘要

FIELD: experimental biology. SUBSTANCE: it is suggested to intraperitoneally inject 0.1 mg 0.25%-droperidole solution per 100 g body weight. Then laboratory animal should be placed into flow-type water bath in its individual cage at water temperature being +43 - +45 C. Rectal temperature should reach +42 - +44 0.5 C during 1.5-2 min. Laboratory animal should be kept at this temperature for 20-25 min till thermal shock. The method enables to heat animal body steadily by not including the mechanisms of thermoregulation. EFFECT: higher efficiency. 4 dwg, 1 ex
机译:领域:实验生物学。物质:建议每100克体重腹膜内注射0.1毫克0.25%的双萜类溶液。然后,将实验动物放在其单独笼中的流式水浴中,水温为+43-+45C。直肠温度应在1.5-2分钟内达到+42-+44 0.5C。实验动物应在此温度下保持20-25分钟,直到受到热冲击。通过不包括温度调节机制,该方法能够稳定地加热动物体。效果:更高的效率。 4 dwg,1 ex

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