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Elucidating the metabolism of substances, useful for investigating the degradation of pharmaceuticals, comprises analyzing substances in a liquid reaction system to identify the metabolites by liquid chromatography and mass spectrometry
Elucidating the metabolism of substances, useful for investigating the degradation of pharmaceuticals, comprises analyzing substances in a liquid reaction system to identify the metabolites by liquid chromatography and mass spectrometry
Elucidating the metabolism of substances, comprising analyzing substances in a liquid reaction system to determine the decomposition product, is new. Elucidating the metabolism of substances, comprising analyzing substances in a liquid reaction system to determine the decomposition products, is new. Potential decomposition products are computed in advance according to a set of degrading rules matching the effects of enzymes, to set the conditions for identification in the analysis procedure. The analysis uses a combination of chromatography to separate the liquid components to be identified by mass spectrometry.
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