Polymer membrane, in the case of the biomolecules in the pores for bioaffinity interactions are located, and process for their preparation

摘要

It is a polymer membrane (10), in the case of the pores (11) biomolecules (12) for bioaffinity interactions are located, in which case the pores (11) is substantially in the form of the membrane (10) are formed open channels passing through, and wherein the membrane (10) on the feed side (16) is acted upon with a solution which contains a substance or a mixture of substances and, on the output side (17) consists of a mixture of (19) of the by means of the biomolecules (12) changed product (21) and, if appropriate, an unaltered substance (15) is discharged, as well as a method for the manufacture of such a polymer membrane (10). In this case, in the pores (11) includes means (20) for generating a turbulent flow. In the case of a possible type of the manufacturing process of the polymer membrane (10), the of the membrane (10) solution with corpuscular elements (20) loaded, and then into the pores (11) of the membrane (10) is conducted. Subsequently, the corpuscular elements (20) in the pores (11) a predetermined time at a predeterminable temperature left to react. Finally, the primary membrane (10) then washed with at least one solvent, so that the in the pores of non-adhesive corpuscular elements (20) from the polymer membrane (10) are removed. This is followed by the binding of the biomolecules to the adhering to the pores wall elements corpuscular.