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use of long-chain n - alkyl derivatives of deoxynojirimycin with glucocerebrosidase enzymes to produce a drug for the treatment of glykolipiden accumulation related krankheiten
use of long-chain n - alkyl derivatives of deoxynojirimycin with glucocerebrosidase enzymes to produce a drug for the treatment of glykolipiden accumulation related krankheiten
A combination drug therapy is disclosed for the treatment of a patient affected with Gaucher's disease or other such glycolipid storage diseases. The method comprises administering to said patient a therapeutically effective amount of both a N-alkyl derivative of deoxynojirimycin (DNJ) and a glucocerebrosidase enzyme to alleviate or inhibit the glycolipid storage disease. The alkyl group has from about two to about 20 carbon atoms and preferably is butyl, nonyl or decyl.
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